Sodium bicarbonate for severe metabolic acidaemia

Bicarbonate therapy in severe metabolic acidosis.

The utility of bicarbonate administration to patients with severe metabolic acidosis remains controversial. Chronic bicarbonate replacement is obviously indicated for patients who continue to lose bicarbonate in the ambulatory setting, particularly patients with renal tubular acidosis syndromes or diarrhea. In patients with acute lactic acidosis and ketoacidosis, lactate and ketone bodies can b...

Severe acidosis and hyperpotassemia treated with sodium bicarbonate infusion.

H YPERPOTASSEMIA is a serious and often fatal complication of advaniced reiial insufficiency. Its principal lethal action is its depressant effect on the myo(.ardiuin.1 2 In uremia, hyperpotassemia is frequently accompanied by acidosis, hyponatreniia, hypoealeemia, alterations in body water, and changes in cellular imetabolism.3 Correction of these associated electrolyte abn orinalities is ofte...

Comment on “Sodium Bicarbonate Therapy in Patients with Metabolic Acidosis”

Metabolic acidosis occurs when a relative accumulation of plasma anions in excess of cations reduces plasma pH. Replacement of sodium bicarbonate to patients with sodium bicarbonate loss due to diarrhea or renal proximal tubular acidosis is useful, but there is no definite evidence that sodium bicarbonate administration to patients with acute metabolic acidosis, including diabetic ketoacidosis,...

Sodium bicarbonate

Major uses Sodium bicarbonate is a main constituent of baking soda/powder. Baking powder is composed of 30% of sodium bicarbonate, with cornstarch, sodium aluminium sulfate, calcium acid phosphate, and calcium sulfate [1]. Sodium bicarbonate may be an ingredient of folk remedies containing turpentine, castor oil, lemon and sugar. It is also added to mouthwashes and dentifrices to prevent dental...

Sodium bicarbonate revisited.